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MECFA Blog

Translate Bio Prioritizes Development of CF Therapy MRT5005, Other Lung Disease Candidates

Translate Bio is going to focus on the development of potential therapies to treat pulmonary diseases, including its lead candidate,...

MAC Lung Infections Best Treated When Specific Bacterial Species Known, Study Finds

Pulmonary infection with a specific species of the Mycobacterium avium complex (MAC), called Mycobacterium intracellulare, can be...

Lung damage bacteria sniffed out by dogs in cystic fibrosis research

A new study found the animals can detect ultra-low concentrations of pseudomonas, the commonest cause of lung infection in the disease....

Kalydeco’s Safety and Benefits Studied in CF Patients with Severe Lung Disease

Treatment with Kalydeco (ivacaftor) improved lung function, exercise capacity, and sweat chloride concentration in cystic fibrosis (CF)...

Babies Treated with Synagis Show No Lasting Benefits in Lung Health as 7-Year-Olds, Real-world Study

Treating infants with cystic fibrosis (CF) with the antiviral therapy Synagis(palivizumab) does not improve long-term outcomes in lung...

FDA Grants Orphan Drug Status to AR-501, Potential CF Treatment for Chronic Lung Infections

AR-501, an investigational inhaled formulation of gallium citrate to treat chronic lung infections in patients with cystic fibrosis (CF),...

Life-saving designer ‘NINJA virus’ hailed as medical breakthrough in curing infection

A VIRUS cocktail designed to seek and destroy bacteria has cleared a 15-year-old lung transplant patient of an antibiotic-resistant...

Phages, Viruses that Attack Bacteria, Are a Potential Therapy Against Infections, Case Report Sugges

The case report of a cystic fibrosis (CF) patient suggests that phages — viruses that naturally infect and kill bacteria — are a...

Incidence of Non-CF Bronchiectasis is Rising in Germany, Study Reports

The incidence of non-cystic fibrosis bronchiectasis is rising in Germany, which necessitates a better understanding of the economic...

Choline Supplementation Improves Lung Function, Liver Health in CF Patients, Study Shows

Choline supplementation improves lung function and liver health in people with cystic fibrosis (CF), and should be considered as a...

Disease Duration, Flare-ups Affect Mental Health of Non-CF Bronchiectasis Patients, Study Finds

VERTEX’S CF BLOCKBUSTER TRIKAFTA EFFECTIVE IN KIDS 6 TO 11 YEARS OF AGE

A case for improved carrier screening

Vertex to Seek Expanded FDA Approval for Trikafta After Positive Child Safety Data

Vertex’s Kaftrio approved for use in Europe and made accessible on the NHS

Age May Affect Outcomes in Lung Transplant Recipients With Cystic Fibrosis

CFF Funding Will Further ContraFect’s Research Into Alternative for Antibiotics

The search for molecular glue in targeted disease control

Vest Therapy Lowers Risk of Hospitalization in Non-CF Bronchiectasis, Study Says

Harvard is working with Boston hospitals to test existing cystic fibrosis drug to help coronavirus p