Oral therapy as safe, effective as insulin in cystic fibrosis-related diabetes
Patients with cystic fibrosis-related diabetes treated with oral repaglinide for 24 months experienced improvements in HbA1c and...
Garlic Compound Could Kill Superbugs
Garlic can do more than ward off vampires. It appears an active sulphurous compound, called ajoene, in the allium can help fight...
Kalydeco Seen as Safe in Treating Young Children, Ages 1 to 2, in Phase 3 Trial, Vertex Reports
Kalydeco (ivacaftor) is safe and effective in 1- and 2-year-olds with cystic fibrosis (CF), Vertex Pharmaceuticals reported based on data...
New Simple Test Could Help Cystic Fibrosis Patients Find Best Treatment
These are nasospheroids that developed from a CF patient's nasal tissue in a dish. UNC researchers are using them to screen the...
GLPG2222 Plus Kalydeco Shows Positive Clinical Results in Phase 2 Trial, Galapagos Reports
Adding investigational CFTR corrector GLPG2222 safely improved disease parameters in cystic fibrosis (CF) patients treated with Kalydeco...
Galapagos Cystic Fibrosis Drug Enters Phase I, Triggering €8.5M Payout
Galapagos will receive a $10M (€8.5M) milestone payment from its collaborator, AbbVie, after their cystic fibrosis candidate started a...
Supine posture changes lung volumes and increases ventilation heterogeneity in cystic fibrosis
Abstract Introduction Lung Clearance Index (LCI) is recognised as an early marker of cystic fibrosis (CF) lung disease. The effect of...
Advances in the Prevention and Treatment of MRSA in Patients with Cystic Fibrosis
Active research and special expertise at Cleveland Clinic’s Adult CF Center Methicillin-resistant Staphylococcus aureus (MRSA) increases...
Galapagos Initiates Phase 1 Trial to Evaluate CF Corrector GLP3221 in Healthy Volunteers
Galapagos has initiated a Phase 1 clinical trial in healthy volunteers to evaluate a new C2 corrector, called GLPG3221, developed for the...