Computer-designed Enzyme May Help to Kill P. aeruginosa in Biofilms
An enzyme produced using computer design, in combination with the antibiotic tobramycin, efficiently kills Pseudomonas aeruginosa, a...
Translate Bio Continues Trial of Inhaled Cystic Fibrosis mRNA Despite Setback
Translate Bio says it is continuing its Phase I/II trial of its inhaled mRNA cystic fibrosis (CF) candidate MRT5005 despite it showing a...
Translate Bio’s MRT5005 Shows Safety and Tolerability at Multiple Doses in Trial
Translate Bio’s ongoing Phase 1/2 clinical trial investigating MRT5005, its candidate inhalation therapy for cystic fibrosis (CF), found...
Analysis of GI Tract Finds High CFTR Gene Activity in Small Intestine
Molecular analysis of single cells lining the digestive tract found high CFTR activity — the gene associated with cystic fibrosis (CF) —...
Living with an invisible illness
I often describe the disease I’m living with as an invisible illness. If you walk by me in the grocery store, or see me dropping my...
Microorganisms utilize vile methodology to vanquish antibody that battle cystic fibrosis
University of Montana researchers and their partners have found a slimy strategy used by bacteria to conquer antibiotics and other...
Lonodelestat Safely Blocks Inflammatory Marker in CF Patients in Early Trial
Lonodelestat (also known as POL6014), Santhera Pharmaceuticals’ investigational therapy to treat chronic lung inflammation, was safe and...
Girls With CF Need Reproductive Counseling, Study Asserts
Female adolescents with cystic fibrosis (CF) should be offered contraceptive counseling and informed about pregnancy risks, a long-term...
ELX-02 Restores CFTR Activity in Organoids With G542X Mutations, Study Finds
ELX-02 restored the levels and function of CFTR — the defective protein in CF — in “mini-organs,” or organoids, derived from patients...
The Middle East CF Association
The Middle East CF Association (MECFA) is working to make lives better for people with cystic fibrosis. Christine Noke is the co-founder...
